Xavier Salvatella

Institut de Recerca Biomèdica (IRB), Barcelona

  • CAIXARESEARCH
    AWARDEE

    Xavier Salvatella Giralt
    Institut de Recerca Biomèdica (IRB), Barcelona
    Principal Investigator

  • PROJECT TITLE

    Modulation of Tau seeding and pathology in tauopathies by BBB-nanocarriers, epitope selective vaccination and ectoPrP Tau receptors bodies.

  • CONSORTIUM

  • PROFILE

    Xavier Salvatella is a Group Leader at the Laboratory of Molecular Biophysics at the Institute for Research in Biomedicine - IRB Barcelona. He holds a degree in Chemistry from the Universities of Barcelona (Bsc, PhD) and London (MSc) and has worked with Michele Vendruscolo and Christopher Dobson at the Department of Chemistry of the University of Cambridge, where he has been a Research Fellow. He was elected as a Research Fellow at Clare Hall, University of Cambridge and was awarded an ICREA Researcher position. Xavier’s general research interests lie at the interface between Chemistry and Biology and have focused in the recent past on understanding how the structure and dynamics of biomacromolecules relate to disease. (Read full CV).

  • RESEARCH
    INTERESTS

    In the last few years I have focused my interest in studying how proteins lacking a well-defined three-dimensional structure, known as intrinsically disordered proteins, perform their functions. More specifically, my laboratory has sought to understand how the sequences of this class of proteins encode specific functions, how these are affected by mutations and under which circumstances it may be possible to inhibit them with drug-like small molecules. Our laboratory is multidisciplinary and combines biophysics with cell/chemical biology as well as with theory/simulations, often in collaboration.

  • CONTACT INFO

    Institut de Recerca Biomèdica (IRB),
    Parc Científic de Barcelona
    C/ Baldiri Reixac 10
    08028 Barcelona
    Tel.: (+34) 93 402 04 59

    Email: [email protected]
    Twitter: @xsalvatella1