David Andreu

Universitat Pompeu Fabra (UPF), Spain

  • CAIXARESEARCH
    AWARDEE

    David Andreu
    Universitat Pompeu Fabra (UPF), Spain
    Fighting Zika virus with antiviral peptides and conjugates translocating blood-placental and blood-brain barriers
    Project leader

  • CONSORTIUM

    • Miguel Castanho
      Instituto de Medicina Molecular (iMM), Portugal
      Co-leader

    • Andrea Thompson da Poian
      Instituto de Bioquímica Médica Leopoldo de Meis, Brasil

  • HIGHLIGHTS OF
    THE PROJECT

    We have developed peptide-porphyrin conjugates able to cross both the blood-brain and the blood-placental barriers to delivery the antiviral (porphyrin) payloads. In vitro and in vivo characterization of these platforms as anti-Zika virus agents will be discussed.

  • PROFILE

    David Andreu is professor of Chemistry at Pompeu Fabra University, Barcelona, where he leads the protein chemistry and proteomics group, with focus on peptide-based vaccines and pharmaceuticals. He is the current president of the European Peptide Society and the editor-in-chief of Drugs of the Future.

  • RESEARCH
    INTERESTS

    Peptide/protein medicinal chemistry, proteomics, antimicrobials, drug delivery, peptide-based vaccines

  • REFERENCES
    OR LINKS

    • Mendonça DA, et al. Bioconjugate Chem 32:1067-1077 (2021).

    • Todorovski T, et al. Pharmaceutics 14:738. (2022).

  • CONTACT INFO

    Departament de Medicina i Ciències de la Salut
    Dr. Aiguader, 88
    08003 Barcelona
    Spain
    Tel.: +34 93 316 08 68

    https://www.upf.edu/uprot/