Bruno Costa-Silva

Fundaçao Champalimaud, Lisbon

  • CAIXARESEARCH
    AWARDEE

    Bruno Costa-Silva
    Fundaçao Champalimaud, Lisbon
    Principal Investigator

  • PROJECT TITLE

    Defining the role of exosome-secreted micropeptides in pancreatic cancer.

  • CONSORTIUM

    • María Abad (PL)
      Fundació Hospital Universitari Vall d’Hebron Institut de Recerca (VHIO), Barcelona

    • Héctor Peinado Selgas
      Fundación Centro Nacional de Investigaciones Oncológicas Carlos III (CNIO), Madrid

  • PROFILE

    We investigate new ways Extracellular Vesicles (EVs) regulate cell signaling, tumor progression, and treatment response. My research group started in 2016 to develop new technological platforms for clinical EV biomarker studies. A vesicle flow cytometry method for expedited EV study in non-processed biofluids has identified important EV biomarkers in pancreatic, breast, colorectal, and clear cell renal cell carcinomas. In unpublished research, we are assessing the diagnostic/prognostic value of new EV protein biomarkers linked to liver metastatic colorectal and pancreatic cancer and their stroma. We also study EVs as regulators of soluble proteins involved in oncologic and non-oncologic diseases. (Read full CV).

  • RESEARCH
    INTERESTS

    His research interest are related to:

    Cancer Metastasis, Tumor Microenvironment, Cancer immunity.

  • CONTACT INFO

    Champalimaud Foundation
    Avenida de Brasilia, Doca de Pedrouços
    Lisbon 1400-038
    Tel.: (+351) 210 480 200

    Email: [email protected]