Santiago Ramón y Cajal

Santiago Ramón y Cajal
Vall d'Hebron Institut de Recerca (VHIR), Spain
Exploiting post-transcriptional regulation to uncover novel vulnerabilities of metastasic cells
Principal investigator

• Fátima Gebauer
  Center for Genomic Regulation (CRG), Spain
  Project leader

• Maria Soengas
  Centro Nacional de Investigaciones Oncológicas (CNIO), Spain
  Co-leader

Santiago Ramón y Cajal is Director of Translational Molecular Pathology at the Vall d'Hebron Institute de Recerca (VHIR). Experience of 25 years as Professor and researcher in Universities of Spain, USA and Canada. Pathologist with training in hospitals of Madrid and Yale and chair of one of the most actives Pathology Departments, in Spain.

https://www.linkedin.com/in/santiago-ramon-y-cajal-agüera-3686482a/

Combing pathology and molecular biology, the aim of our group is to unravel the molecular mechanisms in cancer progression and chemotherapeutic drug resistance.

Our research focuses on:

Cellular Stress related to Cancer:
- Validation and characterization of novel Mnk1/2 inhibitors.
- Characterization of ITGB3 as a potential therapeutic target.

Intra tumor heterogeneity and clonal cooperation:
Taking advantage of having the expertise and availability of primary tumors in the Pathology department and the molecular and cell biological expertise in the research group, we are in a privileged position to study the different aspects of tumor biology at the pathological and molecular level at the same time.

Keywords: pathology, cancer, tumor heterogeneity, clonal cooperation, cellular stress

Department of Pathology
Vall d'Hebron University Hospital
Autonoma University of Barcelona
Passeig de la Vall d'Hebron, 119
08035 Barcelona
Spain
Tel: +34 93 274 68 24

www.vallhebron.com