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Summary of results 2018

Results of the Call

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  • DATOS

    Information concerning the HR17 grant application process and the results are presented below: number of projects submitted, pre-selected and selected by thematic area and category, as well as the territorial distribution of the budget for the selected projects.

    HEALTH RESEARCH 2017 CALL FOR PROPOSALS - INFORMATION

    HR17 Budget

    €12,000,000

    Number of projects presented

    785

    Number of projects evaluated

    785

    Number of projects preselected

    77

    Number of projects selected

    20

    Table 1: General information of Health Research 2017 Call for Proposals.

    Figure 1: Budget distribution by territory

    Figure 1: Budget distribution by territory

    THEMATIC AREA PROJ. PRESENTED PROJ. PRESELECTED (PEER REVIEW) PROJ. SELECTED (EXPERT PANEL)

    Cardiovascular disease

    86

    15

    17,44%

    4

    4,65%

    Neuroscience

    236

    15

    6,36%

    5

    2,12%

    Infectious disease

    123

    16

    13,01%

    4

    3,25%

    Oncology

    177

    16

    9,04%

    4

    2,26%

    Other biomedical areas

    163

    15

    9,20%

    3

    1,84%
      785 77 9,81% 20 2,55%

    Table 2: % of the preselected and selected projects compared to the presented projects in each thematic area.

    THEMATIC AREA PROJ. PRESENTED PROJ. PRESELECTED (PEER REVIEW) PROJ. SELECTED (EXPERT PANEL)

    Cardiovascular disease

    Category A

    53

    61,63%

    8

    53,33%

    3

    75,00%

    Category B

    33

    38,37%

    7

    46,67%

    1

    25,00%

    Total

    86

    10,96%

    15

    19,48%

    4

    20,00%

    Neuroscience

    Category A

    173

    73,31%

    13

    86,67%

    5

    100,00%

    Category B

    63

    26,69%

    2

    13,33%

    0

    0,00%

    Total

    236

    30,06%

    15

    19,48%

    5

    25,00%

    Infectious disease

    Category A

    87

    70,73%

    11

    68,75%

    3

    75,00%

    Category B

    36

    29,27%

    5

    31,25%

    1

    25,00%

    Total

    123

    15,67%

    16

    20,78%

    4

    20,00%

    Oncology

    Category A

    127

    71,75%

    10

    62,50%

    3

    75,00%

    Category B

    50

    28,25%

    6

    37,50%

    1

    25,00%

    Total

    177

    22,55%

    16

    20,78%

    4

    20,00%

    Other biomedical areas

    Category A

    108

    66,26%

    7

    46,67%

    1

    33,33%

    Category B

    55

    33,74%

    8

    53,33%

    2

    66,67%

    Total

    163

    20,76%

    15

    19,48%

    3

    15,00%
     

     

    		 785

     

    		 77

     

    		 20

     

    Table 3: % of A and B projects compared to the total number of projects of each thematic area. % of each thematic area over the presented, preselected and selected projects.

Evaluation process

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  • REMOTE EVALUATION PHASE

    • The proposals were evaluated by a total of 256 experts: at least three per project

    • Proposals were assigned through a process of matching between assessors and projects, taking into account the thematic area, disciplines and keywords.

    • The final score for each project has been adjusted based on two standardization coefficients related to the strictness of each evaluator and the level of coincidence in the matching process.

    • There were 24 proposals with a discrepancy of more than 2.5 points and with the possibility of passing to the interview phase, which were evaluated by a fourth evaluator. The mean score was calculated taking into account the four standardized scores.

  • INTERVIEW PHASE

    The top fifteen proposals (sixteen in the event of a tie) per thematic area according to the ranking established according to the remote evaluation scores proceeded to this phase.

    The interviews were evaluated by panels made up of six to eight experts selected for their excellence and area of expertise, seeking a balance between basic, clinical and translational profiles.

    The process adopted was as follows:

    • Face-to-face interviews where the project will be presented followed by questions.

    • Discussion and assignment of grades by the members of the panel.

    • Individual review of grades by each evaluator and presentation of the initial ranking of projects.

    • Discussion, deliberation and, if necessary, adjustment of the grades by members of the panel.

    • Presentation of the final ranking.

  • LIST

Summary of selected projects

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CODE PROJECT TITLE PROJECT LEADER HOST INSTITUTION PARTNER INSTITUTIONS THEMATIC AREA CATEGORY BUDGET (€)

HR17- 00016

Readying immune cells prior to disease-inducing encounters

Francisco Sánchez-Madrid

Centro Nacional de Investigaciones Cardiovasculares (CNIC)

N/A

Infectious disease

A

499.731

HR17- 00040

Understanding muscle regenerative decline with aging

Pura Muñoz-Cánoves

Universitat Pompeu Fabra (UPF)

N/A

Other biomedical areas

A

496.630

HR17- 00092

Metastasis Cell Fate Mapping

Roger Gomis Cabre

Institute for Research in Biomedicine (IRB)

N/A

Oncology

A

489.400

HR17- 00094

Eradicating prostate cancer metastasis before clinical manifestation

Arkaitz Carracedo 

CIC bioGUNE

University of Cambridge (UK), Fundação Champalimaud (Lisboa), CIC biomaGUNE, Basurto Hospital

Oncology

A

499.915

HR17- 00149

A Translational Model of Antibody-mediated Synaptic Disease: Symptoms, Neuronal Circuits, and the Mechanisms of Memory Loss and Recovery

Josep Dalmau Obrador

Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)

N/A

Neuroscience

A

498.718

HR17- 00199

Towards a universal therapeutic vaccine against chronic virus infections

Andreas Meyerhans

Universitat Pompeu Fabra (UPF)

IrsiCaixa

Infectious disease

A

484.316

HR17- 00221

Genomic and epigenomic drivers of disease evolution in chronic lymphocytic leukemia. Targets for clinical intervention.

Elías Campo 

Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)

Universidad de Oviedo (UNIOVI), Barcelona Supercomputing Center (BSC)

Oncology

B

999.270

HR17- 00231

Regenerating photoreceptors in human retinal organoids to establish a treatment for Retinitis Pigmentosa

Maria Pia Cosma 

Fundació Centre de Regulació Genòmica (CRG)

Institute for Bioengineering of Catalonia (IBEC), Instituto Barraquer

Neuroscience

A

499.519

HR17- 00232

Exploiting post-transcriptional regulation to uncover novel vulnerabilities of metastatic cells

Fátima Gebauer Hernández

Fundació Centre de Regulació Genòmica (CRG)

Centro Nacional de Investigaciones Oncológicas (CNIO)

Oncology

A

499.980

HR17- 00247

The antibody immune response during vascular remodeling

Almudena Rodríguez Ramiro

Centro Nacional de Investigaciones Cardiovasculares (CNIC)

Fundación Jimenez Diaz

Cardiovascular disease

A

499.963

HR17- 00264

Plasmodium Exploitation of Liver-specific Methionine Metabolism

Maria M. Mota

Instituto de Medicina Molecular (IMM), Lisboa

N/A

Infectious disease

A

499.950

HR17- 00267

Somatic Mutation-driven Clonal Hematopoiesis in Atherosclerosis - International Consortium

Valentín Fuster

Centro Nacional de Investigaciones Cardiovasculares (CNIC)

University of Virginia (UVA)

Cardiovascular disease

B

999.896

HR17- 00268

Therapeutic targeting of MBNL microRNAs as innovative treatments for myotonic dystrophy

Ruben Artero-Allepuz

Universitat de Valencia

University of Oxford (UK), Institute for Bioengineering of Catalonia (IBEC), Institut IMAGINE (France), Institute Biodonostia, ASEM & Myotonic Dystrophy Foundation

Other biomedical areas

B

997.024

HR17- 00323

Optical dissection of cortical circuits for sensory expectations

Leopoldo Petreanu

Fundação Champalimaud, Lisboa

N/A

Neuroscience

A

499.708

HR17- 00409

Fighting Zika virus with antiviral peptides and conjugates translocating blood-placental and blood-brain barriers

David Andreu Martínez

Universitat Pompeu Fabra (UPF)

Instituto de Medicina Molecular (IMM), Instituto de Bioquímica Médica Leopoldo de Meis

Infectious disease

B

777.250

HR17- 00513

Modulation of age-dependent neuromelanin accumulation as a novel therapeutic strategy for Parkinson’s disease and brain aging

Miquel Vila Bover

Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca (VHIR)

N/A

Neuroscience

A

466.004

HR17- 00527

Therapeutic targeting of the neutrophil clock in cardiovascular disease

Andrés Hidalgo Alonso

Centro Nacional de Investigaciones Cardiovasculares (CNIC)

Universidad Complutense de Madrid (UCM), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)

Cardiovascular disease

A

499.998

HR17- 00539

Identifying and testing the metabolites generated by two psychoactive gut bacteria to alter brain function and behavior

Carlos Vidal Ribeiro

Fundação Champalimaud, Lisboa

N/A

Neuroscience

A

463.694

HR17- 00595

Organismal role of the ER membrane complex: a conserved machinery required for membrane protein biogenesis.

Colin Adrain

Calouste Gulbenkian Foundation, Lisboa

Institute of Chemical and Biological Technology (ITQB-NOVA, Lisboa), Institute of Organic Chemistry and Biochemistry of the CAS (Czech Republic)

Other biomedical areas

B

960.769

HR17- 00627

Dissecting the functional role of  the  epicardium metabolism  during heart  development and repair after myocardial infarction

Ofelia María Martínez Estrada

Fundació Bosch i Gimpera (UB)

Fundació Hospital Universitari Vall d'Hebron Institut de Recerca (VHIR), Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP)

Cardiovascular disease

A

438.100
Projects awarded in collaboration with the Fundación Luzón

HR17- 00777

Activation of the resolution programs of inflammation as a novel therapeutic approach for the treatment of amyotrophic lateral sclerosis

Rubèn López Vales

Universitat Autònoma de Barcelona (UAB)

N/A

Neuroscience

A

500000
Projects awarded in collaboration with the Fundação para a Ciência e a Tecnologia, I.P. within the “Iniciativa Ibérica de Investigaçao e Inovaçao Biomédica, i4b"

HR17- 00523

Adenosine A2A receptors as a new opportunity to manage and detail the neurobiology of emotional distress

Rodrigo A. Cunha

Centro de Neurociências e Biologia Celular (CNC), Coimbra

N/A

Neuroscience

A

333516

HR17- 00634

A Transdisciplinary Approach to the Identification of Personalized Biomarkers and Therapeutic Targets for Chronic Pulmonary Aspergillosis

Agostinho Albérico Rodrigues de Carvalho

Universidade do Minho

Fundación Universitaria San Pablo (CEU), Foundation for Research and Technology-Hellas, Jena University Hospital and Radboudumc

Infectious disease

B

999027

HR17- 00601

Exosomal fat-liver axis in nonalcoholic fatty liver disease: function and targeting

Rui Eduardo Mota Castro

Universidade de Lisboa

Instituto Biodonostia, École polytechnique fédérale de Lausanne (EPFL) and CIC bioGUNE

Other biomedical areas

A

500000

HR17- 00636

Sequential Cardiac Resynchronization Therapy

Joaquim Adelino Correia Ferreira Leite Moreira

Universidade do Porto

N/A

Cardiovascular disease

A

369248