CaixaResearch Health call

Selected projects 2024

Cardiovascular and associated metabolic diseases

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    A new therapeutic strategy to combat heart disease

    Guadalupe Sabio

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    Towards regenerative cell therapy for type 1 diabetes

    Lorenzo Pasquali

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    Study of the mechanism that triggers a rare autoimmune disease with childhood onset

    Philippe Pierre

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    Generation of human organs from stem cells in animal hosts

    Xabier Aranguren

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    Towards a better understanding of obesity-related liver disease

    Antonio Vidal

Infectious diseases

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    How does the parasite that causes sleeping sickness invade tissues?

    Luísa Figueiredo

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    Study of gamma-delta T cells to develop new immunotherapies against malaria and tuberculosis

    Bruno Silva-Santos

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    A new strategy to modulate T-lymphocyte action and prevent hyperreactive immune responses

    Marc Veldhoen

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    A new strategy to tackle the bacteria that causes tuberculosis

    Tiago Beites

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    New antimalarial drugs based on a mechanism of action linked to the biology of the Plasmodium parasite

    Xavier Fernàndez-Busquets

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    New strategy to combat malaria by targeting a weak point in the biology of the parasite that causes it

    Ruth Pérez

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    New biomarkers to predict which patients will develop invasive pulmonary aspergillosis

    Agostinho Carvalho

Neuroscience

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    Advances in the understanding of neurodegenerative diseases related to mitochondrial DNA replication

    Rafael Fernández Leiro

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    Search for a cure for a lethal degenerative genetic disease that affects children

    Aurora Pujol

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    A new, more effective therapeutic strategy to treat cerebral arteriovenous malformations

    Marc Ribó

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    Towards a cure for Machado-Joseph disease, a rare inherited neurodegenerative disorder

    Patrícia Maciel

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    A synthetic retina to restore vision in cases of blindness due to retinitis pigmentosa

    Pia Cosma

Oncology

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    Better understanding the plasticity of metastatic tumour cells to combat breast cancer

    Roger Gomis

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    Machine learning methods to improve CAR-T therapies for multiple myeloma

    Felipe Prosper

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    How to prevent tumour cells from metastasising in colorectal cancer

    Eduard Batlle

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    Towards new RNA therapies to treat one of the most lethal forms of liver cancer

    Puri Fortes

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    Study of DNA entanglements in tumour cells to develop new tools for cancer diagnosis and treatment

    Felipe Cortés

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    Better understanding of how breast tumour metastases form to prevent them

    Ana Luisa Correia

Enabling technologies

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    A replica of a colon tumour ecosystem on a chip to study the efficacy of immunotherapies

    Xavier Trepat

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    New precision immunotherapies against pancreatic cancer

    María J. Vicent

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    A bacterial therapy to combat pulmonary metastasis

    Luis Serrano

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    Map of genetic mutations in the SOD1 protein that cause ALS to improve early diagnosis and treatment

    Benedetta Bolognesi

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    Early detection of neurodegenerative diseases through the study of tau protein aggregates

    Ana Pina

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    A new strategy to expand accessibility of CAR-T cancer therapies

    Marc Güell