The metabolism, key to understanding non-alcoholic fatty liver

Antonio Zorzano

  • PROJECT LEADER

    Antonio Zorzano

  • HOST ORGANIZATION,
    COUNTRY

    Fundació Institut de Recerca Biomèdica (IRB Barcelona), Spain

  • DESCRIPTION

    Obesity and diabetes are two public health pandemics that have contributed to the increase in chronic liver diseases, among which non-alcoholic fatty liver is the most prevalent.

    This condition is difficult to diagnose and has no treatment. In addition, the accumulation of fat in the liver cells can lead to cirrhosis or liver cancer over the years.

    The project investigates certain metabolism markers that will enable the development of new diagnostic tools and therapeutic targets for one of the most serious forms of fatty liver, non-alcoholic steatohepatitis.

  • PARTNER ORGANIZATIONS

    • Fundació Institut d'Investigació Sanitària Pere Virgili (IISPV), Spain

    • Universitat de Barcelona, Spain

  • PROJECT TITLE

    Phospholipid biosynthesis and transport between endoplasmic reticulum and mitochondria: understanding their essential role in liver disorders

  • BUDGET

    €997,014