Towards new therapies against colorectal cancer

Maite Huarte

  • PROJECT LEADER

    Maite Huarte

  • HOST ORGANIZATION,
    COUNTRY

    Centro de Investigación Médica Aplicada (CIMA), Universidad de Navarra, Spain

  • DESCRIPTION

    Colorectal cancer is the second most frequent tumour in men and women in Spain and one of those with the highest incidence in the world. Many of these tumours have DNA replication problems, which cause damage in their genome.

    It has recently been observed that long non-coding RNAs (lncRNAs), molecules that regulate gene expression, contribute to cancer cells’ ability to replicate.

    The project investigates how lncRNAs influence the development of colon cancer, knowledge that will help identify new therapeutic strategies against this type of tumours.

  • PARTNER ORGANIZATIONS

    • Centro Nacional de Investigaciones Oncológicas (CNIO), Spain

    • Centro Nacional de Biotecnología CNB-CSIC, Spain

  • PROJECT TITLE

    Understanding lncRNAs in replicative stress and colorectal cancer: from cancer biology to single-molecules

  • BUDGET

    €995,200