Roger Gomis

Roger Gomis
Institut de Recerca Biomèdica (IRB Barcelona), Spain
Metastasis cell fate mapping
Project leader

Dr. Gomis is an ICREA Research Professor and a member of the Oncology Program at the Institute for Research in Biomedicine (IRB) Barcelona, where he is Group Leader of the research group “Growth Control and Cancer Metastasis”. In 2012 he founded Inbiomotion as an ICREA and IRB Barcelona spin-off company from his research. Inbiomotion provides a unique companion diagnostic solution, to address an urgent and unmet medical need in the personalized adjuvant treatment of early-stage breast cancer. He has been a postdoctoral fellow at Memorial Sloan-Kettering Cancer Center in Prof. Joan Massagué's laboratory.

https://www.linkedin.com/in/roger-gomis-6a8ab420/

Although metastasis is the leading cause of cancer death, we are still ill-prepared to fight it. Chemotherapy targets high-proliferating rather than the low-proliferating metastatic cells—allowing these to spread from the primary tumor to distant sites, where they resist conventional treatments, proliferate, and cause vital organ failure. We and others have helped to simplify our understanding of metastasis as an orderly sequence of basic steps, which allows us to rationalize the biological properties required for metastatic disease. We know that cancer cells must orchestrate diverse cellular functions to overcome the difficulties of transiting into the metastatic cascade; these functions are highly dependent on the interactions between the metastatic cell, the tumour, and host stroma. We now need a better understanding of steps of the kinetics and mechanisms that regulate tissue-specific metastasis progression, as a prerequisite for developing effective therapies in the future.

IRB Barcelona
Parc Científic de Barcelona
C/ Baldiri Reixac, 10
08028 Barcelona
Spain
Tel.: +34 93 402 02 50

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